Steroidal Glycosides from the Seeds of Hyoscyamus niger L

Antimicrobial activity of the seeds of Hyoscyamus niger L. (Henbane) on microorganisms isolated from urinary tract infections

Objective: The methanol extracts obtained from the seeds of Hyoscyamus niger L. (Solanaceae) were investigated for their antimicrobial activities against the pathogens causing complicated urine tract infections. Methods: The seeds of plant were extracted with aqueous 60% methanol. The extract was screened against urinary tract pathogens (Enterococcus faecalis, Escherichia coli, Klebsiella pneum...

cDNA encoding tropinone reductase-II from Hyoscyamus niger.

Two stereospecific NADPH-dependent reductases, TR-I and TR-11, constitute a branching point in the biosynthesis of tropane alkaloids. TR-I catalyzes the stereospecific reduction of tropinone to tropine (Koelen and Gross, 1982), whereas TR-I1 reduces tropinone to pseudotropine (Drager et al., 1988). We previously characterized TRs that had been purified from cultured roots of Hyoscyamus niger (H...

[On the problem of henbane (Hyoscyamus niger L.) poisoning in children].

Steroidal glycosides from the aerial part of Asclepias incarnata L. II.

Thirty new steroidal glycosides were obtained from the aerial part of Asclepias incarnata L. (Asclepiadaceae). These glycosides were confirmed to have lineolon, isolineolon, 12-O-acetyllineolon, 12-O-(Z)-cinnamoyllineolon, metaplexigenin, 15 beta-hydroxylineolon, 15 beta-hydroxyisolineolon, 16 alpha-hydroxyisolineolon, 12-O-tigloyl-16 alpha-hydroxyisolineolon as the aglycone and 2,6-dideoxyhexo...

Steroidal glycosides from the underground parts of Allium ursinum L. and their cytostatic and antimicrobial activity.

The aim of this study was the isolation and structural elucidation of steroidal glycosides from the underground parts of ramson Allium ursinum L. The structures of the isolated compounds were established based upon chromatographic methods and 1D- and 2D-NMR, MS and IR analyses. The mixture of two steroidal saponins: (25R)-spirost-5-en-3b-ol tetrasaccharide and (25R)-spirost-5, 25(27)-dien-3b-ol...